‘Artificial spermatid'-mediated genome editingâ€
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz087
Abstract: Abstract For years, extensive efforts have been made to use mammalian sperm as the mediator to generate genetically modified animals; however, the strategy of sperm-mediated gene transfer (SMGT) is unable to produce stable and diversified… read more here.
Keywords: genome editing; haescs; spermatid mediated; mediated genome ... See more keywords
Transcriptome profiles and chromatin states in mouse androgenetic haploid embryonic stem cells.
Sign Up to like & getrecommendations! Published in 2023 at "Cell proliferation"
DOI: 10.1111/cpr.13436
Abstract: Haploid embryonic stem cells (haESCs) are derived from the inner cell mass of the haploid blastocyst, containing only one set of chromosomes. Extensive and accurate chromatin remodelling occurs during haESC derivation, but the intrinsic transcriptome… read more here.
Keywords: haploid; haescs; transcriptome profiles; stem ... See more keywords