Articles with "hairless rats" as a keyword



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Utility of hairless rats as a model for predicting transdermal pharmacokinetics in humans

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Published in 2019 at "Xenobiotica"

DOI: 10.1080/00498254.2019.1703059

Abstract: Abstract This study investigated the use of HWY hairless rats to predict human plasma concentrations of drugs following dermal application. Utilizing a deconvolution method, pharmacokinetic parameters (e.g. in vivo absorption rates) were determined for six… read more here.

Keywords: hair follicle; hairless rats; hairless; hydrophilic compounds ... See more keywords