Mapping the cell-membrane proteome of the SKBR3/HER2+ cell line to the cancer hallmarks
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272384
Abstract: The hallmarks of biological processes that underlie the development of cancer have been long recognized, yet, existing therapeutic treatments cannot prevent cancer from continuing to be one of the leading causes of death worldwide. This… read more here.
Keywords: cell; cell membrane; membrane proteome; hallmark ... See more keywords
CHG: A Systematically Integrated Database of Cancer Hallmark Genes
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DOI: 10.3389/fgene.2020.00029
Abstract: Background The analysis of cancer diversity based on a logical framework of hallmarks has greatly improved our understanding of the occurrence, development and metastasis of various cancers. Methods We designed Cancer Hallmark Genes (CHG) database… read more here.
Keywords: genes chg; hallmark; database; hallmark genes ... See more keywords
Identification and Validation of Prognostic Related Hallmark ATP-Binding Cassette Transporters Associated With Immune Cell Infiltration Patterns in Thyroid Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.781686
Abstract: ATP-binding cassette (ABC) transporters are a large superfamily of membrane proteins that facilitate the translocation of heterogeneous substrates. Studies indicate that ABC transporters may play important roles in various carcinomas. However, the correlation between ABC… read more here.
Keywords: abc transporters; cell infiltration; immune cell; hallmark abc ... See more keywords
Plant homocysteine, a methionine precursor and plant’s hallmark of metabolic disorders
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DOI: 10.3389/fpls.2022.1044944
Abstract: Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid, which arises from redox-sensitive methionine metabolism. In plants, Hcy synthesis involves both cystathionine β-lyase and S-adenosylhomocysteine hydrolase activities. Thus, Hcy itself is crucial for de novo methionine… read more here.
Keywords: homocysteine; methionine; hcy; amino acid ... See more keywords
Genetic Clonality as the Hallmark Driving Evolution of Non-Small Cell Lung Cancer
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DOI: 10.3390/cancers14071813
Abstract: Simple Summary Limited knowledge about NSCLC evolution has affected therapeutic strategies for many decades. The application of NGS-based techniques to studies on ITH has provided genetic insight into the contribution of clonality primary seeding, as… read more here.
Keywords: non small; clonality; treatment; hallmark ... See more keywords