Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma.
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DOI: 10.1182/blood.2022015926
Abstract: Unique molecular vulnerabilities have been identified in the aggressive MCD/C5 genetic subclass of diffuse large B cell lymphoma (DLBCL). However, the pre-malignant cell-of-origin exhibiting MCD-like dependencies remains elusive. In this study, we examined animals carrying… read more here.
Keywords: cell; lymphoma; hallmark genetic; genetic lesions ... See more keywords