Articles with "hallmark tdp" as a keyword



Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202412054

Abstract: Cytoplasmic aggregation of transactive response DNA‐binding protein 43 (TDP‐43) is a hallmark of amyotrophic lateral sclerosis (ALS) and occurs in 57% of Alzheimer's disease (AD) cases. TDP‐43 regulates RNA processing, including cryptic exon splicing. Here,… read more here.

Keywords: cryptic splicing; gap43; hallmark tdp; cryptic exon ... See more keywords