SYNTHESIS AND HALOCYCLIZATION OF 3-CYANO-4,6-DIMETHYL-2-PYRIDONE ALLYL DERIVATIVES
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5078
Abstract: The sequence of condensation, alkylation, and halocyclization reactions during the synthesis of the target 2,3-dihydro[1,3]oxazolo[3,2- a ]pyridinium salts was investigated. The effect of basic catalysis on the chemoselectivity of the reaction of malononitrile with acetylacetone… read more here.
Keywords: cyano dimethyl; cyano; halocyclization; dimethyl pyridone ... See more keywords
Flavin-dependent halogenases catalyze enantioselective olefin halocyclization
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DOI: 10.1038/s41467-021-23503-3
Abstract: Halocyclization of alkenes is a powerful bond-forming tool in synthetic organic chemistry and a key step in natural product biosynthesis, but catalyzing halocyclization with high enantioselectivity remains a challenging task. Identifying suitable enzymes that catalyze… read more here.
Keywords: dependent halogenases; flavin dependent; enantioselective olefin; catalyze enantioselective ... See more keywords