Constructing a multienzyme cascade redox-neutral system for the synthesis of halogenated indoles.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00811d
Abstract: Inspired by biocatalytic retrosynthesis, a multienzyme cascade system containing alcohol dehydrogenase, flavin-dependent halogenase and flavin reductase was developed for the synthesis of several halogenated indoles starting from amino alcohol. This redox-neutral system not only omitted… read more here.
Keywords: system; neutral system; redox neutral; multienzyme cascade ... See more keywords
4F-Indole Enhances the Susceptibility of Pseudomonas aeruginosa to Aminoglycoside Antibiotics
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04519-22
Abstract: Infections caused by Pseudomonas aeruginosa have become a major public health crisis. Its resistance to existing antibiotics causes clinical infections that are hard to cure. In this study, we found that halogenated indoles in combination… read more here.
Keywords: infections caused; pseudomonas aeruginosa; aeruginosa pao1; regulatory effect ... See more keywords