Design, Synthesis, and Evaluation of Carbonate-Linked Halogenated Phenazine-Quinone Prodrugs with Improved Water-Solubility and Potent Antibacterial Profiles.
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DOI: 10.1021/acsinfecdis.2c00558
Abstract: Pathogenic bacteria have devastating impacts on human health as a result of acquired antibiotic resistance and innate tolerance. Every class of our current antibiotic arsenal was initially discovered as growth-inhibiting agents that target actively replicating… read more here.
Keywords: potent antibacterial; halogenated phenazine; quinone; carbonate linked ... See more keywords