5-(Halomethyl)uridine derivatives as potential antitumor radiosensitizers: A DFT study
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DOI: 10.1016/j.cplett.2017.12.062
Abstract: Abstract Considering the fact that the efficiency of the uridine-5-methyl radical in producing cytotoxic DNA intrastrand cross-link lesions is greatly higher than that of the uridine-5-yl radical, the radiosensitizing action of 5-(halomethyl)uridines (5-XCH2U, X = F, Cl,… read more here.
Keywords: derivatives potential; antitumor radiosensitizers; uridine derivatives; halomethyl uridine ... See more keywords