The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior
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DOI: 10.1038/s41398-020-01014-x
Abstract: The mammalian target of rapamycin (mTOR) is a ubiquitously expressed serine/threonine kinase protein complex (mTORC1 or mTORC2) that orchestrates diverse functions ranging from embryonic development to aging. However, its brain tissue-specific roles remain less explored.… read more here.
Keywords: haloperidol induced; rapamycin mtor; mammalian target; mtor ... See more keywords
Protective effect of hesperetin against haloperidol-induced orofacial dyskinesia and catalepsy in rats
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DOI: 10.1080/1028415x.2017.1338549
Abstract: Objectives: The present study was designed to evaluate the effect of hesperetin on haloperidol-induced orofacial dyskinesia and catalepsy in Wistar male albino rats. Methods: Haloperidol (1 mg/kg, ip) was administered for 21 successive days to induce… read more here.
Keywords: haloperidol induced; orofacial dyskinesia; haloperidol; dyskinesia catalepsy ... See more keywords
Haloperidol-induced isolated lingual dystonia
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DOI: 10.1136/bcr-2021-242272
Abstract: A 28-year-old woman presenting with agitation and mania with psychotic features developed symptoms of isolated lingual dystonia shortly after the initiation of a haloperidol concentrate regimen. read more here.
Keywords: isolated lingual; haloperidol induced; lingual dystonia; induced isolated ... See more keywords
Role of Aqueous Extract of the Wood Ear Mushroom, Auricularia polytricha (Agaricomycetes), in Avoidance of Haloperidol-lnduced Catalepsy via Oxidative Stress in Rats.
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DOI: 10.1615/intjmedmushrooms.2019030351
Abstract: Haloperidol-induced catalepsy is an animal model of a psychotic disorder that may be associated with neurodegeneration and free radical damage. Auricularia polytricha is effective in both prevention and treatment of numerous types of neurological disorders.… read more here.
Keywords: haloperidol; 400 600; aqueous extract; auricularia polytricha ... See more keywords
Dopamine Improves Low Gamma Activities in the Dorsal Striatum of Haloperidol-induced Motor Impairment Mice
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DOI: 10.21873/invivo.13080
Abstract: Abstract Background/Aim: The dorsal striatum is a brain area integrating information for movement output. The local field potentials (LFPs) reflect the neuronal activity that can be used for monitoring brain activities and controlling movement. Materials… read more here.
Keywords: low gamma; movement; dorsal striatum; motor ... See more keywords
Propionate Protects Haloperidol-Induced Neurite Lesions Mediated by Neuropeptide Y
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2018.00743
Abstract: Haloperidol is a commonly used antipsychotic drug for treating schizophrenia. Clinical imaging studies have found that haloperidol can cause volume loss of human brain tissue, which is supported by animal studies showing that haloperidol reduces… read more here.
Keywords: haloperidol induced; induced neurite; propionate; effect ... See more keywords
Haloperidol-Induced Immediate Early Genes in Striatopallidal Neurons Requires the Converging Action of cAMP/PKA/DARPP-32 and mTOR Pathways
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911637
Abstract: Antipsychotics share the common pharmacological feature of antagonizing the dopamine 2 receptor (D2R) which is abundant in the striatum and involved in both the therapeutic and side effects of this drugs class. Pharmacological blockade of… read more here.
Keywords: early genes; immediate early; action; darpp mtor ... See more keywords