Articles with "haloprotac" as a keyword



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Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader

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Published in 2019 at "ACS Chemical Biology"

DOI: 10.1021/acschembio.8b01016

Abstract: Inducing post-translational protein knockdown is an important approach to probe biology and validate drug targets. An efficient strategy to achieve this involves expression of a protein of interest fused to an exogenous tag, allowing tag-directed… read more here.

Keywords: degradation; rapid reversible; haloprotac; biology ... See more keywords