The golden (Syrian) hamster as a model for the study of reproductive biology: Past, present, and future
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12241
Abstract: The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent that belongs to the Cricetidae family. It has several unique features that are advantageous for the study of reproductive and developmental biology, including a consistent… read more here.
Keywords: hamster model; golden syrian; study reproductive; syrian hamster ... See more keywords
SARS-CoV-2 airway infection results in the development of somatosensory abnormalities in a hamster model
Sign Up to like & getrecommendations! Published in 2023 at "Science Signaling"
DOI: 10.1126/scisignal.ade4984
Abstract: Although largely confined to the airways, SARS-CoV-2 infection has been associated with sensory abnormalities that manifest in both acute and chronic phenotypes. To gain insight on the molecular basis of these sensory abnormalities, we used… read more here.
Keywords: sensory abnormalities; infection; hamster model; pain ... See more keywords
Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model
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DOI: 10.1128/mbio.00028-20
Abstract: Infections with New World hantaviruses are associated with high case fatality rates, and no specific vaccine or treatment options exist. Furthermore, the biology of the hantaviral GnGc complex, its antigenicity, and its fusion machinery are… read more here.
Keywords: biology; monoclonal antibodies; andes virus; hamster model ... See more keywords
Idol Depletion Protects against Spontaneous Atherosclerosis in a Hamster Model of Familial Hypercholesterolemia
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1889632
Abstract: Inducible degrader of low-density lipoprotein (LDL) receptor (Idol) is an E3 ubiquitin ligase coded by Idol, the target gene of liver X receptor (LXR), which primarily mediates the ubiquitination and lysosomal degradation of low-density lipoprotein… read more here.
Keywords: idol depletion; hamster model; atherosclerosis; idol ... See more keywords
Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1080897
Abstract: Background Drug repurposing is a fast and effective way to develop drugs for an emerging disease such as COVID-19. The main challenges of effective drug repurposing are the discoveries of the right therapeutic targets and… read more here.
Keywords: inflammation; hamster model; methotrexate; cov entry ... See more keywords
Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.945583
Abstract: Severe coronavirus disease (COVID-19) is accompanied with acute respiratory distress syndrome & pulmonary pathology, and is presented mostly with inflammatory cytokine release, dysregulated immune response, skewed neutrophil/ lymphocyte ratio, and hypercoagulable state. Though vaccinations have… read more here.
Keywords: prophylactic treatment; glycyrrhiza glabra; hamster model; pathology ... See more keywords
Activity of a Carbohydrate-Binding Module Therapy, Neumifil, against SARS-CoV-2 Disease in a Hamster Model of Infection
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DOI: 10.3390/v14050976
Abstract: The rapid global spread of severe acute respiratory coronavirus 2 (SARS-CoV-2) has resulted in an urgent effort to find efficacious therapeutics. Broad-spectrum therapies which could be used for other respiratory pathogens confer advantages, as do… read more here.
Keywords: hamster model; binding module; therapy; carbohydrate binding ... See more keywords
The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15051133
Abstract: The ongoing emergence of SARS-CoV-2 virus variants remains a source of concern because it is accompanied by the potential for increased virulence as well as evasion of immunity. Here we show that, although having an… read more here.
Keywords: infection; hamster model; golden syrian; syrian hamster ... See more keywords