Suppression of Sebum Production by Vemurafenib Through Paradoxical ERK Activation Resulted in the Inhibition of the mTOR Pathway in 5α‐Dihydrotestosterone‐Differentiated Hamster Sebocytes In Vitro
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DOI: 10.1111/exd.70150
Abstract: Vemurafenib, a low‐molecular‐weight BRAF inhibitor, effectively treats cutaneous melanoma with the BRAFV600E mutation, but it causes skin disorders such as dry skin with high frequency. As one of the factors causing skin dryness is a… read more here.
Keywords: hamster sebocytes; dht; production; sebum production ... See more keywords