Bone Mass, Bone Microstructure and Biomechanics in Patients with Hand Osteoarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4046
Abstract: The impact of primary hand osteoarthritis (HOA) on bone mass, microstructure, and biomechanics in the affected skeletal regions is largely unknown. HOA patients and healthy controls (HCs) underwent high‐resolution peripheral quantitative computed tomography (HR‐pQCT). We… read more here.
Keywords: vbmd; biomechanics; bone; hoa ... See more keywords
DNA methylation of bone morphogenetic protein 7 in leukocytes as a possible biomarker for hand osteoarthritis: A pilot study
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.25963
Abstract: Hand osteoarthritis (HOA), characterized by an earlier onset age and reduced susceptibility to mechanical stress compared with knee and hip osteoarthritis, is considered a suitable disease for identifying predictive biomarkers of osteoarthritis. In particular, DNA… read more here.
Keywords: dna methylation; methylation; hoa; hand osteoarthritis ... See more keywords
Biomarkers of hand osteoarthritis
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology International"
DOI: 10.1007/s00296-017-3864-5
Abstract: Hand osteoarthritis (OA) is a common degenerative joint disorder leading to substantial pain and disability. The most severe subtype is erosive hand OA characterized by an abrupt onset, local inflammation, subchondral erosions and worse outcomes… read more here.
Keywords: biomarkers hand; disease; potential biomarkers; hand ... See more keywords
A randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis - the HUMOR trial.
Sign Up to like & getrecommendations! Published in 2018 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2018.02.899
Abstract: OBJECTIVE To assess the efficacy of adalimumab in patients with erosive hand osteoarthritis (OA). METHOD Patients >50 years old, meeting the American College of Rheumatology (ACR) criteria for hand OA, with pain >50 on 100 mm… read more here.
Keywords: trial; hand osteoarthritis; hand; erosive hand ... See more keywords
Performance of the Michigan Hand Outcomes Questionnaire in hand osteoarthritis.
Sign Up to like & getrecommendations! Published in 2018 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2018.07.018
Abstract: OBJECTIVE To investigate the performance of the Michigan Hand Outcomes Questionnaire (MHQ) in hand osteoarthritis (OA) by evaluating truth, discrimination and feasibility. DESIGN Symptomatic hand OA patients from the Hand Osteoarthritis in Secondary Care (HOSTAS)… read more here.
Keywords: hand osteoarthritis; hand; pain function; performance ... See more keywords
Guidelines for the conduct of pharmacological clinical trials in hand osteoarthritis: Consensus of a Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2017.12.003
Abstract: OBJECTIVES To gather expert opinion on the conduct of clinical trials that will facilitate regulatory review and approval of appropriate efficacious pharmacological treatments for hand osteoarthritis (OA), an area of high unmet clinical need. METHODS… read more here.
Keywords: working group; hand; clinical trials; trials hand ... See more keywords
Reliability and agreement of proton density-weighted vs. gadolinium-enhanced T1-weighted MRI in hand osteoarthritis. An OMERACT MRI special interest group reliability exercise.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2021.05.007
Abstract: OBJECTIVES To compare reliabilities of assessing synovitis in hand osteoarthritis (OA) using Magnetic Resonance Imaging (MRI) with/without gadolinium (Gd). METHODS Three readers scored synovitis on non-enhanced two-dimensional (2D) proton density (PD)-weighted MRI and Gd-enhanced (3D)… read more here.
Keywords: hand osteoarthritis; proton density; mri; reliability ... See more keywords
Erosive hand osteoarthritis: latest findings and outlook
Sign Up to like & getrecommendations! Published in 2022 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-021-00747-3
Abstract: Osteoarthritis (OA) most commonly affects knee joints, and the next most commonly affected sites are the hands and hips. Three distinct hand OA phenotypes have been described: erosive hand OA (EHOA), nodal hand OA —… read more here.
Keywords: latest findings; ehoa; hand; erosive hand ... See more keywords
Efficacy of hydroxychloroquine in hand osteoarthritis
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DOI: 10.1097/md.0000000000023517
Abstract: Abstract Background: Symptoms of hand osteoarthritis result in activity limitations and lower quality of life. Hydroxychloroquine, which has been used successfully in the treatment of many autoimmune diseases, can suppress inflammation and might also be… read more here.
Keywords: hydroxychloroquine hand; medicine; hand; efficacy hydroxychloroquine ... See more keywords
Effect of Exercises on Clinical Outcomes of Patients With Hand Osteoarthritis
Sign Up to like & getrecommendations! Published in 2021 at "Orthopaedic Nursing"
DOI: 10.1097/nor.0000000000000729
Abstract: Hand osteoarthritis (OA) is one of the most common degenerative joint disorders seen in the adult population. The prevalence of hand OA increases with age and is more common among women than in men. The… read more here.
Keywords: exercises clinical; hand; outcomes patients; hand osteoarthritis ... See more keywords
FRI0520 Discovery of potential biomarkers for the diagnosis of erosive and nodal hand osteoarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.4495
Abstract: Background Two different phenotypes of hand osteoarthritis (HOA) have been defined: nodal hand osteoarthritis (NHOA) and erosive hand osteoarthritis (EHOA). NHOA involve bone enlargement of the underlying interphalangeal joints, which may typically give rise to… read more here.
Keywords: psa; ehoa; hand; hand osteoarthritis ... See more keywords