The EF-Hand Protein CALML6 Suppresses Antiviral Innate Immunity by Impairing IRF3 Dimerization.
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DOI: 10.1016/j.celrep.2019.01.030
Abstract: The transcription factor IRF3 is phosphorylated in response to viral infection, and it subsequently forms a homodimer and translocates into the nucleus to induce the transcription of genes important for antiviral immunity, such as type I… read more here.
Keywords: immunity; dimerization; antiviral innate; innate immunity ... See more keywords