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hapE and hmg1 Mutations Are Drivers of cyp51A-Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate

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Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.05188-22

Abstract: Triazole resistance is an important cause of treatment failure and high mortality rates for A. fumigatus human infections. Although Cyp51A-associated mutations are frequently identified as the cause of A. fumigatus triazole resistance, they do not… read more here.

Keywords: clinical isolate; hape hmg1; resistance; triazole resistance ... See more keywords