The Role of Donor Selection for a Second Allogeneic Stem Cell Transplantation in Patients with AML Relapsing after a First Transplant; A Study on Behalf of the Acute Leukemia Working Party of EBMT
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.134
Abstract: Introduction Recurrent disease is the major cause of treatment failure after allogeneic stem cell transplantation (SCT) in patients with AML. Second SCT (SCT2) is a valid treatment option in this setting but outcome is relatively… read more here.
Keywords: sct2; haplo; transplantation; donor ... See more keywords
Post transplant cyclophosphamide based haplo-identical transplant versus umbilical cord blood transplant; a meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyz099
Abstract: OBJECTIVES Both haplo-identical transplant (haplo) and umbilical cord transplant (UC) are valuable graft options for patients without available matched relative. Previous studies showed inconsistent outcomes comparing Post transplant Cyclophosphamide based haplo (PTCy-haplo) and UC; therefore,… read more here.
Keywords: ptcy haplo; transplant; versus; haplo ... See more keywords
A prospective observational study of immune reconstitution following transplantation with post‐transplant reduced‐dose cyclophosphamide from HLA‐haploidentical donors
Sign Up to like & getrecommendations! Published in 2019 at "Transplant International"
DOI: 10.1111/tri.13494
Abstract: Allogeneic hematopoietic cell transplantation (HCT) from HLA‐haploidentical donors with post‐transplantation high‐dose cyclophosphamide (PT/Cy‐haplo) now predominates worldwide. However, to our knowledge, no prospective study has compared immune reconstitution after PT/Cy‐haplo with that after conventional HCT. The… read more here.
Keywords: dose cyclophosphamide; haploidentical donors; transplantation; hla haploidentical ... See more keywords
The effect of donor type on outcomes in adults with acute myeloid leukemia after reduced‐intensity hematopoietic peripheral blood cell transplant – a retrospective study
Sign Up to like & getrecommendations! Published in 2020 at "Transplant International"
DOI: 10.1111/tri.13659
Abstract: We retrospectively analyzed outcomes in patients with acute myeloid leukemia (AML) receiving reduced‐intensity conditioning (RIC) hematopoietic stem cell transplants (HCT) from a peripheral blood (PB) source. We identified 46 haploidentical HCT (haplo), 59 matched unrelated… read more here.
Keywords: myeloid leukemia; donor; reduced intensity; peripheral blood ... See more keywords
Association between haploidentical hematopoietic stem cell transplantation combined with an umbilical cord blood unit and graft-versus-host disease in pediatric patients with acquired severe aplastic anemia
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Hematology"
DOI: 10.1177/20406207221134409
Abstract: Background: Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) based on granulocyte colony-stimulating factor plus anti-thymocyte regimens (‘Beijing Protocol’) provides a salvage treatment for patients of acquired severe aplastic anemia (SAA) in China. However, graft-versus-host disease (GVHD)… read more here.
Keywords: cord; hsct; haplo; gvhd ... See more keywords
Influence of Donor Type (sibling vs matched-unrelated donor vs haplo-identical donor vs cord blood) on Outcomes after Clofarabine-Based Reduced-Intensity Conditioning Allograft for Myeloid Malignancies
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-112369
Abstract: Background: Recently, we have reported the good results of a clofarabine-based reduced-intensity conditioning (RIC) regimen for peripheral blood stem cell (PBSC) allografts, using either matched (Le Bourgeois, ASH 2017) or haploidentical (haplo) donors (Chevallier, ASH… read more here.
Keywords: donor; sibling mud; haplo; type ... See more keywords
Allogeneic Hematopoietic Stem Cell Transplantation in Patients of 65 Years or Older: A Monocenter Analysis on 252 Patients
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-131845
Abstract: Advanced hematologic malignancies in older patients are unmet medical needs due to increased incidence in the aging population and the lack of effective treatment. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents the only potential curative… read more here.
Keywords: cell; age; donor; haplo ... See more keywords
Alternative Donor Hematopoietic Cell Transplantation for Pediatric, Adolescent and Young Adult with Hematological Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-141334
Abstract: Hematopoietic cell transplantation (HCT) is the only potential curative option for many advanced hematologic diseases. Pediatrics, adolescent and young adult (PAYA) patients overall have less pre-HCT comorbidity or organ toxicity and lower transplant related morbidity… read more here.
Keywords: consultancy; hct; compared mud; donor ... See more keywords
Favorable Outcomes in Pediatric R/R-ALL Following Immunotherapy with CAR-T and UCB Combined to TCR αβ -Depleted Haplo-HSCT
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DOI: 10.1182/blood-2024-205593
Abstract: Background and aim: TCRαβ-depleted HLA-haploidentical stem cell transplantation(TCD Haplo-HSCT) represents a promising curative option for children with relapsed and refractory acute lymphoblastic leukemia (R/R-ALL). However, disease recurrence remains the primary cause of treatment failure. We… read more here.
Keywords: tcr depleted; haplo; car; haplo hsct ... See more keywords
Comparable outcomes of haploidentical, sibling, and unrelated donor transplantation for adult T-ALL in second remission: a study from the global committee and ALWP of the EBMT
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DOI: 10.1182/blood-2025-2526
Abstract: Introduction T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive precursor lymphoid neoplasm that accounts for 20% to 25% of all adult ALL cases. Allogeneic hematopoietic cell transplantation (allo-HCT) is typically recommended for adults with T-ALL… read more here.
Keywords: haplo; haplo msd; group; gvhd ... See more keywords
Outcomes of HLA-matched unrelated versus haploidentical hematopoietic cell transplantation in acute leukemia: A multicenter observational study in Brazil facilitated by the CIBMTR
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DOI: 10.1182/blood-2025-5981
Abstract: Background: While several studies from high-income countries have evaluated hematopoietic cell transplantation (HCT) using haploidentical related (Haplo) and HLA-matched unrelated donors (MUD), prospective data from low- and middle-income countries remain scarce. Brazil, home to one… read more here.
Keywords: relapse; haplo; hla matched; haplo mud ... See more keywords