Haploidentical vs matched unrelated donor transplantation for acute myeloid leukemia in remission: A prospective comparative study
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DOI: 10.1002/ajh.25993
Abstract: Despite comparable outcomes of haploidentical transplants (Haplo‐HSCT) with HLA‐matched unrelated transplants (MUD‐HSCT) in retrospective comparisons, few studies have prospectively compared Haplo‐HSCT with MUD‐HSCT in AML. Here, we prospectively compared the outcomes of Haplo‐HSCT with MUD‐HSCT… read more here.
Keywords: haplo hsct; mud hsct; remission; hsct ... See more keywords
Haploidentical transplantation for pediatric patients with acquired severe aplastic anemia
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DOI: 10.1038/bmt.2016.281
Abstract: Techniques for haploidentical hematopoietic stem cell transplantation (haplo-HSCT) to treat severe aplastic anemia (SAA) have recently improved, but no protocol has been evaluated in a large number of pediatric patients. Fifty-two children with SAA received… read more here.
Keywords: aplastic anemia; haplo hsct; transplantation; pediatric patients ... See more keywords
Idarubicin-intensified haploidentical HSCT with GvHD prophylaxis of ATG and basiliximab provides comparable results to sibling donors in high-risk acute leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Bone Marrow Transplantation"
DOI: 10.1038/bmt.2017.100
Abstract: We designed a novel haploidentical hematopoietic stem cell transplantation (haplo-HSCT) system using idarubicin (IDA) intensified conditioning regimens and combination of antithymocyte globulin and basiliximab for GvHD prophylaxis. The outcomes of 110 high-risk acute leukemia patients… read more here.
Keywords: risk acute; high risk; hsct; acute leukemia ... See more keywords
Comparison of efficacy and health-related quality of life of first-line haploidentical hematopoietic stem cell transplantation with unrelated cord blood infusion and first-line immunosuppressive therapy for acquired severe aplastic anemia
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DOI: 10.1038/s41375-020-0933-7
Abstract: We retrospectively compared the efficacy and health-related quality of life (HRQoL) of (1) first-line haploidentical hematopoietic stem cell transplantation (haplo-HSCT, n = 146) combined with unrelated cord blood (UCB) infusion and (2) first-line immunosuppressive therapy (IST,… read more here.
Keywords: line; first line; infusion; group ... See more keywords
Comparison of transplant outcomes between haploidentical transplantation and single cord blood transplantation in non‐remission acute myeloid leukaemia: A nationwide retrospective study
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DOI: 10.1111/bjh.18530
Abstract: Allogeneic haematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for some patients with acute myeloid leukaemia (AML) who are refractory to chemotherapy. Cord blood transplantation (CBT) is a reasonable option in such cases… read more here.
Keywords: non remission; acute myeloid; transplantation; myeloid leukaemia ... See more keywords
Myeloablative Haploidentical Transplantation Is Superior to Chemotherapy for Patients with Intermediate-risk Acute Myelogenous Leukemia in First Complete Remission
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DOI: 10.1158/1078-0432.ccr-18-1637
Abstract: Purpose: Although myeloablative HLA haploidentical hematopoietic stem cell transplantation (haplo-HSCT) following pretransplant anti-thymocyte globulin (ATG) and granulocyte colony-stimulating factor (G-CSF) stimulated grafts (ATG+G-CSF) has been confirmed as an alternative to HSCT from HLA-matched sibling donors… read more here.
Keywords: postremission; chemotherapy; risk; hsct ... See more keywords
Pharmacokinetics of mycophenolic acid after haplo-hematopoietic stem cell transplantation in Japanese recipients
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DOI: 10.1177/1078155220980815
Abstract: Purpose Mycophenolate mofetil (MMF), a mycophenolic acid (MPA) prodrug, is used to prevent graft-versus-host disease (GVHD) in hematopoietic stem cell transplantation (HSCT). Although previous studies have reported that enterohepatic circulation (EHC) of MPA, which is… read more here.
Keywords: mycophenolic acid; cell transplantation; hsct; haplo hsct ... See more keywords
Administration of BPX-501 Following α-T and B-Cell Depleted Haplo-HSCT in Children with Transfusion-Dependent Thalassemia
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DOI: 10.1182/blood-2018-166
Abstract: Background Allogeneic hematopoietic stem cell transplantation (HSCT) from an HLA-identical sibling has been shown to cure most children with transfusion-dependent b-thalassemia major. Results obtained using an HLA-partially matched (haploidentical, haplo) donor have been historically less… read more here.
Keywords: bpx 501; cell depleted; depleted haplo; haplo hsct ... See more keywords
Stem Cell Transplantation in Advanced Stage Sickle Cell Disease with Haploidentical T-Cell Depleted PBSC Yields Comparable Outcomes to Matched Sibling Donor Bone Marrow: Results of a Pilot Study
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DOI: 10.1182/blood-2018-99-114695
Abstract: Background: Sickle cell disease (SCD) is an inherited disorder with an estimate of 300,000 affected newborns per year worldwide. Despite improvements in preventive measures and conventional therapy, substantial morbidity and mortality, resulting in a reduced… read more here.
Keywords: group; hsct; donor; haplo hsct ... See more keywords
Cytokine Release Syndrome after Peripheral Blood T-Cell Replete Haploidentical Transplantation Is Not Prevented By Dexamethasone and Limits Its Full-Outpatient Conduction
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DOI: 10.1182/blood-2018-99-116996
Abstract: Introduction: Our center has implemented an outpatient-based peripheral blood haploidentical HSCT (haplo-HSCT) program since 2012. Cytokine release syndrome (CRS) associated with T-cell replete haplo-HSCT is characterized by fever and high levels of inflammatory cytokines with… read more here.
Keywords: day; haplo hsct; crs; cell replete ... See more keywords
Disease Risk Comorbidity Index for Patients Receiving Haploidentical Allogeneic Hematopoietic Transplantation
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DOI: 10.1182/blood-2019-124371
Abstract: Purpose or Background: We aimed to develop a disease risk comorbidity index (DRCI) based on Disease Risk Index (DRI) and Hematopoietic Cell Transplantation-Specific Comorbidity Index (HCT-CI) in patients receiving haploidentical hematopoietic stem cell transplantation (haplo-HSCT).… read more here.
Keywords: comorbidity index; risk; disease risk; disease ... See more keywords