Have haploidentical transplants replaced umbilical cord transplants for acute leukemias?
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DOI: 10.1097/moh.0000000000000412
Abstract: Purpose of review Haploidentical stem cell transplantation (Haplo SCT) and umbilical cord blood stem cell transplantation (UCB SCT) have emerged over the past two to three decades as viable sources of alternative donor SCT when… read more here.
Keywords: umbilical cord; cord; sct; haplo sct ... See more keywords
The Optimal Alternative Donor Transplant for Pediatric Patients with Acute Leukemia: A Comparison between Alfa-Beta T-Cell and B-Cell Depleted Haplo-SCT and UCBT
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DOI: 10.1182/blood-2018-99-111799
Abstract: Children with acute leukemia (AL) in need of an allograft and lacking an HLA-identical sibling and an HLA-matched unrelated donor, could benefit either from unrelated cord blood transplantation (UCBT) or T-cell depleted haploidentical (haplo) stem… read more here.
Keywords: sct; haplo sct; alfa beta; cell ... See more keywords
Gvhd after PBSC-Haploidentical Stem Cell Transplantation (Haplo-SCT) with Post Transplantation-Cyclophosphamide (PT-Cy)
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DOI: 10.1182/blood.v130.suppl_1.1984.1984
Abstract: T-cell replete Haplo-SCT using PT-Cy as GVHD part of prophylaxis has become a valid option to perform allogeneic transplantation in patients without an available HLA-matched donor. The absence of additional ex vivo procedure has participated… read more here.
Keywords: gvhd; transplantation; haplo sct; stem ... See more keywords
Association of Persistent Minimal Residual Disease with Poor Outcomes of Patients with Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
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DOI: 10.4103/0366-6999.246072
Abstract: Background: Several studies have shown that detection of minimal residual disease (MRD) in acute myeloid leukemia (AML) is an independent prognostic factor. This study aimed to evaluate the significance of dynamic MRD pretransplantation on outcome… read more here.
Keywords: positive mrd; mrd; persistent positive; transplantation ... See more keywords