Cancer Cells Haploinsufficient for ATM Are Sensitized to PARP Inhibitors by MET Inhibition
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DOI: 10.3390/ijms23105770
Abstract: The MET oncogene encodes a tyrosine kinase (TK) receptor. Its activation protects cells from death but also stimulates DNA damage response by triggering excess replicative stress. Transcriptomic classification of cancer cell lines based on MET… read more here.
Keywords: cell; inhibition; met inhibition; haploinsufficient atm ... See more keywords