Enhanced ammonia detoxification to urea in hepatocytes transduced with human aquaporin‐8 gene
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DOI: 10.1002/bit.27901
Abstract: Hepatic ammonia detoxification to urea is critical for the prevention of hyperammonemia and neurological damage. Hepatocyte mitochondrial aquaporin‐8 (AQP8) channels have been involved in ammonia‐derived ureagenesis. Herein, we studied whether the adenoviral gene transfer of… read more here.
Keywords: detoxification urea; haqp8; detoxification; enhanced ammonia ... See more keywords