Expanding the Chemical Space of Drug-like Passerini Compounds: Can α-Acyloxy Carboxamides Be Considered Hard Drugs?
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DOI: 10.1021/acsmedchemlett.2c00420
Abstract: With their three points of diversity, α-acyloxy carboxamides, which are accessible with the Passerini reaction, provide heterogeneity for the preparation of libraries of putative active agents or intermediates used for the formation of more complex… read more here.
Keywords: drug like; expanding chemical; acyloxy carboxamides; hard drugs ... See more keywords