More than 3Rs: the importance of scientific validity for harm-benefit analysis of animal research
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DOI: 10.1038/laban.1220
Abstract: More than 3Rs: the importance of scientific validity for harm-benefit analysis of animal research read more here.
Keywords: validity harm; harm benefit; 3rs importance; scientific validity ... See more keywords
Justifying children and young people’s involvement in social research: Assessing harm and benefit
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DOI: 10.1177/0791603517711860
Abstract: At a time when children and young people’s involvement in research is increasingly the norm, this article reflects on the importance of a well-reasoned and transparent justification for their inclusion or exclusion. It explores the… read more here.
Keywords: children young; research; harm benefit; people involvement ... See more keywords
Downstaging for hepatocellular cancer: harm or benefit?
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DOI: 10.21037/tgh.2017.11.18
Abstract: Downstaging of hepatocellular carcinoma (HCC) to enable liver transplantation has become an area of intense interest and research. It may allow a curative option in patients outside widely accepted transplantation criteria, with outcomes that, in… read more here.
Keywords: downstaging hepatocellular; harm benefit; hepatocellular cancer; gastroenterology ... See more keywords
Rethinking the Appraisal and Approval of Drugs for Fracture Prevention
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DOI: 10.3389/fphar.2017.00265
Abstract: Background: In January 2014, the EMA's Pharmacovigilance Risk Assessment Committee recommended that strontium ranelate no longer be used for osteoporosis. However, EMA's Committee for Medicinal Products for Human Use decided to restrict its use rather… read more here.
Keywords: fracture prevention; drugs fracture; harm benefit; rethinking appraisal ... See more keywords