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Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12010098
Abstract: Two genes are said to have synthetic lethal (SL) interactions if the simultaneous mutations in a cell lead to lethality, but each individual mutation does not. Targeting SL partners of mutated cancer genes can kill…
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Keywords:
synthetic lethal;
harnessing synthetic;
lethal interactions;
personalized medicine ... See more keywords