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Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102600
Abstract: Biomacromolecules have long been at the leading edge of academic and pharmaceutical drug development and clinical translation. With the clinical advances of new therapeutics, such as monoclonal antibodies and nucleic acids, the array of medical…
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Keywords:
nucleic acids;
therapeutic potential;
harnessing therapeutic;
intracellular delivery ... See more keywords
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Published in 2022 at "Small"
DOI: 10.1002/smll.202104783
Abstract: Extracellular vesicles (e.g., exosomes) carrying various biomolecules (e.g., proteins, lipids, and nucleic acids) have rapidly emerged as promising platforms for many biomedical applications. Despite their enormous potential, their heterogeneity in surfaces and sizes, the high…
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Keywords:
potential extracellular;
therapeutic potential;
extracellular vesicles;
biomedical applications ... See more keywords
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Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0224072
Abstract: Messenger RNA (mRNA) and microRNA (miRNA)-based therapeutics have become attractive alternatives to DNA-based therapeutics due to recent advances in manufacture, scalability and cost. Also, RNA-based therapeutics are considered safe since there are no risk of…
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Keywords:
harnessing therapeutic;
delivery;
rna;
based therapeutics ... See more keywords
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Published in 2023 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026623666230328161236
Abstract: Despite significant breakthroughs in cancer treatment, cancer remains a serious global health concern that takes thousands of lives each year. Still, drug resistance and adverse effects are the main problems in conventional cancer therapeutic approaches.…
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Keywords:
peptides cancers;
therapeutic potential;
potential antimicrobial;
antimicrobial peptides ... See more keywords