Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively
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DOI: 10.1093/nar/gkx147
Abstract: Abstract We investigate the mechanistic nature of the Snf2 family protein HARP, mutations of which are responsible for Schimke immuno-osseous dysplasia. Using a single-molecule magnetic tweezers assay, we construct RPA-stabilized DNA bubbles within torsionally constrained… read more here.
Keywords: rpa stabilized; dna; harp; harp closes ... See more keywords