3H-pyrazolo[4,3-f]quinoline haspin kinase inhibitors and anticancer properties.
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DOI: 10.1016/j.bioorg.2018.03.031
Abstract: Histone modification, a post-translational modification of histones and involving various covalent tags, such as methyl, phosphate and acetate groups, affects gene expression and hence modulates various cellular events, including growth and proliferation. Consequently histone-modifying proteins… read more here.
Keywords: kinase inhibitors; pyrazolo quinoline; quinoline haspin; haspin ... See more keywords