Amantadine and Rimantadine Inhibit Hepatitis A Virus Replication through the Induction of Autophagy
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DOI: 10.1128/jvi.00646-22
Abstract: Amantadine, a nonspecific antiviral medication, also effectively inhibits HAV replication. Autophagy is an important cellular mechanism in several virus-host cell interactions. ABSTRACT Hepatitis A virus (HAV) infection is a major cause of acute viral hepatitis… read more here.
Keywords: amantadine rimantadine; replication; hav replication; autophagy ... See more keywords
Drug Screening for Hepatitis A Virus (HAV): Nicotinamide Inhibits c-Jun Expression and HAV Replication
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DOI: 10.1128/jvi.01987-22
Abstract: Drug screening methods targeting HAV IRES-mediated translation with reporter assays are attractive and useful for drug repurposing. Nicotinamide (vitamin B3, niacin) has been shown to effectively inhibit HAV replication. ABSTRACT Hepatitis A virus (HAV) infection… read more here.
Keywords: mediated translation; ires mediated; replication; hav replication ... See more keywords