Screening for undiagnosed diabetes in the first trimester of pregnancy: a summary of the evidence
Sign Up to like & getrecommendations! Published in 2017 at "The Lancet"
DOI: 10.1016/s0140-6736(17)32957-4
Abstract: Abstract Background Diabetes in pregnancy is associated with miscarriage, stillbirth, congenital abnormalities, macrosomia, and perinatal mortality. The demographics of the population becoming pregnant have changed (more obese and older women). Therefore, more women are starting… read more here.
Keywords: pregnancy; evidence; undiagnosed diabetes; diabetes first ... See more keywords
23-hydroxybetulinic acid reduces tumorigenesis, metastasis and immunosuppression in a mouse model of hepatocellular carcinoma via disruption of the MAPK signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001325
Abstract: Hepatocellular carcinoma (HCC) shows recurrence and lung metastasis even after treatment. 23-hydroxybetulinic acid (23-HBA), a major active constituent of Pulsatilla chinensis, exhibits potent antitumor activities. We herein investigate the biological effect of 23-HBA on metastasis… read more here.
Keywords: metastasis; signaling pathway; hcc; mapk signaling ... See more keywords
Females perpetrating honour-based abuse: controllers, collaborators or coerced?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Aggression, Conflict and Peace Research"
DOI: 10.1108/jacpr-01-2018-0341
Abstract: The purpose of this paper is to address an emerging international debate about the involvement of females in perpetrating honour-based abuse (HBA). Presenting new empirical data, this study profiles the different roles played by women,… read more here.
Keywords: abuse controllers; perpetrating honour; honour based; based abuse ... See more keywords
4‐Hydroxybenzoic acid is a diffusible factor that connects metabolic shikimate pathway to the biosynthesis of a unique antifungal metabolite in Lysobacter enzymogenes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Microbiology"
DOI: 10.1111/mmi.13619
Abstract: Heat‐stable antifungal factor (HSAF) produced by Lysobacter enzymogenes is a potential lead compound for developing new antibiotics. Yet, how L. enzymogenes regulates the HSAF biosynthesis remains largely unknown. Here, we show that 4‐hydroxybenzoic acid (4‐HBA)… read more here.
Keywords: biosynthesis; production; shikimate pathway; hsaf ... See more keywords
Biosynthesis of the yellow xanthomonadin pigments involves an ATP‐dependent 3‐hydroxybenzoic acid: acyl carrier protein ligase and an unusual type II polyketide synthase pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Microbiology"
DOI: 10.1111/mmi.14064
Abstract: Xanthomonadins are yellow pigments that are produced by the phytopathogen Xanthomonas campestris pv. campestris (Xcc). A pig cluster is responsible for xanthomonadin biosynthesis. Previously, Xcc4014 of the cluster was characterized as a bifunctional chorismatase that… read more here.
Keywords: biosynthesis; hydroxybenzoic acid; xanthomonadin; unusual type ... See more keywords
Heat-Stable Antifungal Factor (HSAF) Biosynthesis in Lysobacter enzymogenes Is Controlled by the Interplay of Two Transcription Factors and a Diffusible Molecule
Sign Up to like & getrecommendations! Published in 2017 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01754-17
Abstract: ABSTRACT Lysobacter enzymogenes is a Gram-negative, environmentally ubiquitous bacterium that produces a secondary metabolite, called heat-stable antifungal factor (HSAF), as an antifungal factor against plant and animal fungal pathogens. 4-Hydroxybenzoic acid (4-HBA) is a newly… read more here.
Keywords: hsaf biosynthesis; molecule; hsaf; hba ... See more keywords
Gastrodin and Gastrodigenin Improve Energy Metabolism Disorders and Mitochondrial Dysfunction to Antagonize Vascular Dementia
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28062598
Abstract: Vascular dementia (VD) is the second most common dementia syndrome worldwide, and effective treatments are lacking. Gastrodia elata Blume (GEB) has been used in traditional Chinese herbal medicine for centuries to treat cognitive impairment, ischemic… read more here.
Keywords: hba; gas; dysfunction; energy metabolism ... See more keywords
p-Hydroxybenzyl Alcohol Antagonized the ROS-Dependent JNK/Jun/Caspase-3 Pathway to Produce Neuroprotection in a Cellular Model of Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14235002
Abstract: Parkinson’s disease (PD) is a progressive disorder that affects brain nerve cells responsible for body motion and remains incurable. p-Hydroxybenzyl alcohol (HBA) is the primary phenolic compound in Gastrodiae Rhizoma, known for its therapeutic benefits… read more here.
Keywords: parkinson disease; caspase; hba; parkinson ... See more keywords
4-Hydroxybenzoic Acid as an Antiviral Product from Alkaline Autoxidation of Catechinic Acid: A Fact to Be Reviewed
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11141822
Abstract: The dark brown mixture resulting from the autooxidation of catechinic acid (CA) (AOCA) has been reported to possess antiviral activity against Herpes Simplex Virus 1 and 2 (HSV-1 and HSV-2). Unfortunately, the constituents of AOCA… read more here.
Keywords: acid; aoca; hba; antiviral activity ... See more keywords