Articles with "hbb" as a keyword



Hyoscine butylbromide significantly decreases motion artefacts and allows better delineation of anatomic structures in mp-MRI of the prostate

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Published in 2017 at "European Radiology"

DOI: 10.1007/s00330-017-4940-7

Abstract: AbstractObjectivesTo prospectively evaluate the effect of hyoscine butylbromide (HBB) on visualisation of anatomical details and motion-related artefacts in mp-MRI of the prostate at 3.0 Tesla.MethodsOne hundred and three consecutive patients (65 ± 10 years) were included in this… read more here.

Keywords: motion; hyoscine butylbromide; hbb; mri prostate ... See more keywords

HBB-deficient Macaca fascicularis monkey presents with human β-thalassemia

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Published in 2019 at "Protein & Cell"

DOI: 10.1007/s13238-019-0627-y

Abstract: β-Thalassemia is a common severe genetic disease caused by mutations in HBB and affects approximately 1.5% of the global population (Origa, 2017). In southern China, the carrier rate of β-thalassemia is as high as 6.43%,… read more here.

Keywords: monkey; hbb; information fig; thalassemia ... See more keywords

Computational and drug target analysis of functional single nucleotide polymorphisms associated with Haemoglobin Subunit Beta (HBB) gene

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Published in 2020 at "Computers in biology and medicine"

DOI: 10.1016/j.compbiomed.2020.104018

Abstract: There is overwhelming evidence implicating Haemoglobin Subunit Beta (HBB) protein in the onset of beta thalassaemia. In this study for the first time, we used a combined SNP informatics and computer algorithms such as Neural… read more here.

Keywords: hbb; subunit beta; beta; haemoglobin subunit ... See more keywords
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Hb Presbyterian (HBB: c.327C>G) in a Nicaraguan Family

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Published in 2017 at "Hemoglobin"

DOI: 10.1080/03630269.2017.1302949

Abstract: Abstract Hemoglobin (Hb) is the protein responsible for oxygen transportation. It is a tetrameric protein comprising two α- and two β-globin subunits. In the literature, a large number of mutations in the α- and β-globin… read more here.

Keywords: hbb; hbb 327; 327c nicaraguan; family ... See more keywords

Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending

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Published in 2024 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkae485

Abstract: Histones are essential for genome compaction and transcription regulation in eukaryotes, where they assemble into octamers to form the nucleosome core. In contrast, archaeal histones assemble into dimers that form hypernucleosomes upon DNA binding. Although… read more here.

Keywords: hbb; dna binding; dna; bdellovibrio bacteriovorus ... See more keywords

Qualitative Insights Into Enhancing Neonatal Resuscitation in Post-Pandemic Vietnam

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Published in 2024 at "Advances in Neonatal Care"

DOI: 10.1097/anc.0000000000001157

Abstract: Background: The neonatal phase is vital for child survival, with a substantial portion of deaths occurring in the first month. Neonatal mortality rates differ significantly between Vietnam (10.52/1000 live births) and the United States (3.27/1000).… read more here.

Keywords: neonatal resuscitation; post; hbb; hbb training ... See more keywords

Hb Palencia: a novel δβδ-type two-way fusion variant with β-globin-like expression levels

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Published in 2018 at "Journal of Clinical Pathology"

DOI: 10.1136/jclinpath-2018-205282

Abstract: Aims Fusion proteins of unequal recombination events at the β-globin locus have pathological effect. The haemoglobin (Hb) variants of type Lepore are fusion proteins characterised by β-like globin chains with a δ-globin (HBD) N-terminus and… read more here.

Keywords: globin; terminus; hbb; hbd ... See more keywords

Association of LRF with MBD3-NuRD Versus MBD2 NuRD Mediates Opposing Effects on Developmental Globin Gene Regulation

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Published in 2024 at "Blood"

DOI: 10.1182/blood-2024-203712

Abstract: Sufficiently high levels of HbF have been shown to ameliorate the pathophysiologic effects of HbS in sickle cell anemia patients bearing the homozygous codon 6 GAG to GTG mutation in the beta globin gene (HBB).Leukemia… read more here.

Keywords: mbd3 nurd; hbb; mbd2 nurd; expression ... See more keywords

Benefits of Targeted Next Generation Sequencing (NGS) for Identification of Newborn Hemoglobinopathies: The California Experience

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Published in 2024 at "Blood"

DOI: 10.1182/blood-2024-206092

Abstract: Introduction Hemoglobinopathies are a heterogenous group of disorders comprised of variants in α-globin (HBA), β-globin (HBB) genes or both. Newborn screening (NBS) is aimed to identify clinically significant hemoglobin disorders and facilitate early delivery of… read more here.

Keywords: diagnosis; deletion; generation sequencing; next generation ... See more keywords
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The effect of hyoscine n- butylbromide on labor progress: A systematic review

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Published in 2020 at "BMC Pregnancy and Childbirth"

DOI: 10.1186/s12884-020-2832-3

Abstract: Background The objective of this systematic review and meta-analysis was to assess the effectiveness of hyoscine n-butylbromide in labor progress. Methods The databases including PubMed, the Cochrane Library, Science-Direct, Scopus and Web of Science were… read more here.

Keywords: hyoscine butylbromide; labor; hbb; systematic review ... See more keywords

Evaluation of Helping Babies Breathe Quality Improvement Cycle (HBB-QIC) on retention of neonatal resuscitation skills six months after training in Nepal

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Published in 2017 at "BMC Pediatrics"

DOI: 10.1186/s12887-017-0853-5

Abstract: BackgroundEach year 700,000 infants die due to intrapartum-related complications. Implementation of Helping Babies Breathe (HBB)-a simplified neonatal resuscitation protocol in low-resource clinical settings has shown to reduce intrapartum stillbirths and first-day neonatal mortality. However, there… read more here.

Keywords: hbb; bag mask; neonatal resuscitation; resuscitation ... See more keywords