Enhanced cancer immunotherapy by microneedle patch-assisted delivery of HBc VLPs based cancer vaccine
Sign Up to like & getrecommendations! Published in 2021 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2021.101110
Abstract: Abstract Tumor vaccines have made a significant breakthrough in clinical trials of cancer therapy, but have shown limited efficacy. Herein, we develop a novel tumor vaccine delivery strategy through a biodegradable microneedle patch (MN), which… read more here.
Keywords: ova hbc; cancer; hbc vlps; tumor ... See more keywords
Development of HBc virus-like particles as modular nanocarrier by intein-mediated trans-splicing.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.10.081
Abstract: Hepatitis B virus core protein (HBc) spontaneously assembles as Virus-like particles (VLPs) in Escherichia coli (E. coli) which is extensively used as a nanocarrier to boost antigen immunogenicity. Genetic fusion of cargo protein with HBc occasionally… read more here.
Keywords: intein mediated; virus like; hbc vlps; hbc ... See more keywords
Early Aβ-HBc virus-like particles immunization had better effects on preventing the deficit of learning and memory abilities and reducing cerebral Aβ load in PDAPP mice.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.07.049
Abstract: For nearly two decades, immunization against the β-amyloid peptide (Aβ) has been investigated as a potential treatment for Alzheimer's disease (AD). Despite some disappointing results in clinic trials, greater significance has been attached by some… read more here.
Keywords: hbc vlps; memory abilities; pdapp mice; learning memory ... See more keywords
Photodynamic Therapy in Combination with the Hepatitis B Core Virus-like Particles (HBc VLPs) to Prime Anticancer Immunity for Colorectal Cancer Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14112724
Abstract: Simple Summary Photodynamic therapy (PDT) by means of a photosensitizer is a clinically used therapeutic treatment in a variety of cancers. To further improve the anti-cancer efficiency of PDT, combination therapy with immune agents is… read more here.
Keywords: hbc vlps; combination; therapy; photodynamic therapy ... See more keywords