Serum, saliva, and gingival tissue human β-defensin levels in relation to retinoic acid use.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontology"
DOI: 10.1002/jper.22-0466
Abstract: BACKGROUND Retinoic acid is an active derivative of vitamin A and regulates the differentiation, proliferation, and antimicrobial peptide expression profiles of human cells. The aim of the present study was to analyze the effect of… read more here.
Keywords: hbd hbd; retinoic acid; hbd; tissue ... See more keywords
Dynamic changes of Th1/Th2/Th17 cytokines and human beta defensin 2 in HIV-infected patients with oral candidiasis during the first year of highly active anti-retroviral therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2018.05.003
Abstract: OBJECTIVE To investigate the change of Th1/Th2/Th17 cytokines and human beta defensin 2 (HBD-2) in HIV-infected patients with oral candidiasis (OC) and gather information about OC-specific immunity. DESIGN During the 1st year of highly active… read more here.
Keywords: hbd; year; infected patients; th1 th2 ... See more keywords
Gingival crevicular fluid levels of Interleukin-22 (IL-22) and human β Defensin-2 (hBD-2) in periodontal health and disease : A correlative study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of oral biology and craniofacial research"
DOI: 10.1016/j.jobcr.2020.07.021
Abstract: Background Interleukin 22(IL-22), a recently identified, Th-22 associated cytokine has a key role in the production of human β defensin-2(hBD-2) and hence an indirect role in innate, nonspecific immunity. Hence this study was conducted as… read more here.
Keywords: crevicular fluid; hbd; gingival crevicular; chronic periodontitis ... See more keywords
Molecular Dynamics Simulations of Human Beta-Defensin Type 3 Crossing Different Lipid Bilayers
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c01803
Abstract: Human β defensin type 3 (hBD-3) is a small cationic cysteine-rich peptide. It has a broad spectrum of antimicrobial activities. However, at high concentrations, it also shows hemolytic activity by interrupting red blood cells. To… read more here.
Keywords: energy; hbd; lipid bilayers; hbd different ... See more keywords
Human beta defensin (HBD) gene copy number affects HBD2 protein levels: impact on cervical bactericidal immunity in pregnancy
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-017-0061-7
Abstract: Human beta defensin 2 (HBD2) is an endogenous mucosal antimicrobial peptide (AMP) upregulated during infection and inflammation. HBD2 is encoded by the DEFB4 gene, which exhibits extensive copy number variation. Previous studies have demonstrated a… read more here.
Keywords: copy number; hbd; number; protein levels ... See more keywords
Immune-microbial crosstalk in oral epithelium: A potential role in oral carcinogenesis?
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz452.024
Abstract: Abstract Background We reported in recent publication that bacterial lipopolysaccharides (LPS) and mast cells are involved in the pathogenesis of the premalignant lesion, oral lichen planus (OLP). However, the mechanisms beyond such effect remain unknown.… read more here.
Keywords: immune microbial; oral epithelium; hbd; role ... See more keywords
Expression of Psoriasin in Human Papillomavirus–Induced Cervical High-Grade Squamous Intraepithelial Lesions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Lower Genital Tract Disease"
DOI: 10.1097/lgt.0000000000000438
Abstract: Objectives Persistent infection with human papillomavirus causes cervical high-grade squamous intraepithelial lesions (HSILs). The role of antimicrobial peptides (AMPs) in premalignant and malignant transformation is not fully understood. In this study, we examined the expression… read more here.
Keywords: expression; hbd; treatment; human papillomavirus ... See more keywords
Gingival Tissue Human Beta-Defensin Levels in Relation to Infection and Inflammation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13227
Abstract: AIM To profile gingival tissue levels of human beta-defensin (hBD)-2 and hBD-3 in relation to gingival inflammation, Th17-related cytokine concentrations, Porphyromonas gingivalis counts, and gingipain and total protease activities. MATERIALS AND METHODS Gingival tissue and… read more here.
Keywords: gingival tissue; beta defensin; hbd; inflammation ... See more keywords
Recombinant Human Erythropoietin Proteins Synthesized in Escherichia coli Cells: Effects of Additional Domains on the in vitro and in vivo Activities
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297919010036
Abstract: The aim of this work was to compare biological activities of three variants of bacterially expressed human recombinant erythropoietin (EPO) with additional protein domains: 6His-s-tag-EPO protein carrying the s-tag (15-a.a. oligopeptide from bovine pancreatic ribonuclease… read more here.
Keywords: hbd; erythropoietin; recombinant human; epo ... See more keywords
Hb Palencia: a novel δβδ-type two-way fusion variant with β-globin-like expression levels
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2018-205282
Abstract: Aims Fusion proteins of unequal recombination events at the β-globin locus have pathological effect. The haemoglobin (Hb) variants of type Lepore are fusion proteins characterised by β-like globin chains with a δ-globin (HBD) N-terminus and… read more here.
Keywords: globin; terminus; hbb; hbd ... See more keywords
REGγ Contributes to Regulation of Hemoglobin and Hemoglobin δ Subunit
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/7295319
Abstract: Hemoglobin (Hb) is a family of proteins in red blood cells responsible for oxygen transport and vulnerable for oxidative damage. Hemoglobin δ subunit (HBD), a member of Hb family, is normally expressed by cells of… read more here.
Keywords: hemoglobin; hbd; via reg; hemoglobin subunit ... See more keywords