Fludarabine inhibits type I interferon-induced expression of the SARS-CoV-2 receptor angiotensin-converting enzyme 2
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00698-5
Abstract: Angiotensin-converting enzyme 2 (ACE2) is the receptor for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV2 and is upregulated after infection with these viruses, which assists the entry of these viruses into the target cells.… read more here.
Keywords: hbe cells; ifn; stat1; ace2 ... See more keywords
Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Inhibiting Ferroptosis Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.845600
Abstract: Silicosis is a fatal occupational lung disease which currently has no effective treatment. Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-inflammatory, anti-oxidant and anti-cancer bioactivity. However, whether DHQ protects against silica-induced lung fibrosis… read more here.
Keywords: hbe cells; silica induced; lung; fibrosis ... See more keywords
Differences in Treatment Response in Bronchial Epithelial Cells from Idiopathic Pulmonary Fibrosis (IPF) Patients: A First Step towards Personalized Medicine?
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020443
Abstract: Idiopathic pulmonary fibrosis (IPF) has a detrimental prognosis despite antifibrotic therapies to which individual responses vary. IPF pathology is associated with oxidative stress, inflammation and increased activation of SRC family kinases (SFK). This pilot study… read more here.
Keywords: hbe cells; ipf; idiopathic pulmonary; expression ... See more keywords