Serum M2BPGi level is a novel predictive biomarker for the responses to pegylated interferon‐α treatment in HBeAg‐positive chronic hepatitis B patients
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25010
Abstract: Serum Mac‐2‐binding protein glycosylation isomer (M2BPGi) level was found to be a useful prognostic marker for hepatitis B e antigen (HBeAg)‐positive chronic hepatitis B (CHB) patients treated with nucleoside/nucleotide analogs (NUCs) therapy, and the aim… read more here.
Keywords: m2bpgi level; serum m2bpgi; treatment; hbeag ... See more keywords
HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2753-8
Abstract: Activation of Kupffer cells (KCs) induced that inflammatory cytokine production plays a central role in the pathogenesis of HBV infection. The previous studies from our and other laboratory demonstrated miRNAs can regulate TLR-inducing inflammatory responses… read more here.
Keywords: mir 155; inflammatory cytokines; expression; hbeag ... See more keywords
Liver Fibrosis in the Natural Course of Chronic Hepatitis B Viral Infection: A Systematic Review with Meta-Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-07009-y
Abstract: Quantitative data are limited on the natural course of liver fibrosis in patients with chronic HBV infection (CHB). To estimate the prevalence of fibrosis status including non-fibrosis, significant fibrosis, advanced fibrosis, and cirrhosis throughout the… read more here.
Keywords: natural course; phase; fibrosis; liver fibrosis ... See more keywords
Chronic viral HBeAg-negative hepatitis B: Epidemiological, clinical and biochemical characteristics in an outpatient descriptive cohort in Burkina Faso
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Epidemiology and Global Health"
DOI: 10.1016/j.cegh.2021.100799
Abstract: Abstract Introduction Our study aimed to describe epidemiological and diagnostic features in an outpatient's cohort with chronic HBeAg-negative hepatitis B. Patients and methods A cross-sectional descriptive study with a retrospective data collection was implemented from… read more here.
Keywords: hbeag; burkina faso; negative hepatitis; hbeag negative ... See more keywords
HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00769-7
Abstract: TO THE EDITOR It is believed that the inherent tolerogenic property of the liver is involved in the chronicity of hepatitis B virus (HBV) infection [1]. However, exposure to HBV in adults usually leads to… read more here.
Keywords: lsecs; hbv; cell activation; hbeag ... See more keywords
HBeAg-induced miR-106b promotes cell growth by targeting the retinoblastoma gene
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-14652-x
Abstract: Chronic HBV infection is a major cause of hepatocellular carcinoma (HCC). The association between hepatitis B “e” antigen (HBeAg) and HCC is well-established by epidemiological studies. Nonetheless, the biological role of HBeAg in HCC remains… read more here.
Keywords: retinoblastoma gene; expression; hbeag; mir 106b ... See more keywords
Frequency of Hepatitis B Virus Envelope Antigen and Antibodies Among Chronic Carriers in Ibadan, Nigeria.
Sign Up to like & getrecommendations! Published in 2021 at "Viral immunology"
DOI: 10.1089/vim.2020.0259
Abstract: Hepatitis B virus (HBV) infection is a major health challenge in sub-Saharan Africa with a prevalence rate of >7%. It is an important clinical problem due to its potential adverse sequelae, including hepatocellular carcinoma. The… read more here.
Keywords: hbv; envelope antigen; hepatitis virus; hbeag ... See more keywords
Role of Innate Immune Regulatory Genes, FOXP3 and FOS in Chronic Hepatitis B Infection.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0145
Abstract: Persistence of hepatitis B virus (HBV) infection leading to chronic infection and its sequalae is responsible for over half a million deaths worldwide. The reason for persistence of chronic hepatitis B (CHB) infection is still… read more here.
Keywords: chb; immune regulatory; infection; chronic hepatitis ... See more keywords
Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13104
Abstract: Hepatitis B e antigen (HBeAg) is an important serological marker of hepatitis B virus (HBV) infection and is associated with higher levels of viraemia, increased risk of infectivity to others and increased risk of hepatocellular… read more here.
Keywords: hepatitis; age; prevalence; age race ... See more keywords
Patterns of HBeAg and HBsAg clearance among a treatment‐naive Alaskan Cohort in a long‐term observational study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13271
Abstract: In this long-term observational study, we examined the patterns of HBsAg reduction in a cohort of patients with HBeAg (+) and (-) chronic hepatitis B (CHB) who achieved spontaneous HBsAg clearance CHB Patients were selected… read more here.
Keywords: log year; hbsag; hbeag; hbsag clearance ... See more keywords
EASL 2025 indications revisited: phase-specific outcomes with and without nucleos(t)ide analogue therapy in chronic hepatitis B virus infection
Sign Up to like & getrecommendations! Published in 2025 at "Gut"
DOI: 10.1136/gutjnl-2025-335449
Abstract: Objective The impact of nucleos(t)ide analogues (NAs) therapy on the long-term outcomes in chronic HBV infection individuals outside 2025 European Association for the Study of the Liver (EASL) strongly recommended treatment indications remains uncertain. We… read more here.
Keywords: hbv; therapy; hcc; hbeag ... See more keywords