Less can be more: A finite treatment approach for HBeAg‐negative chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29821
Abstract: Long-term administration of potent nucleos (t)ide analogs (NAs) is the cornerstone of antiviral therapy for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B, as it reduces liver-related complications by efficiently suppressing viral replication. Although there… read more here.
Keywords: hepatitis; hbeag negative; relapse; negative chronic ... See more keywords
HBV pre‐core mutant in genotype‐D infected children is selected during HBeAg/anti‐HBe seroconversion and leads to HBeAg negative chronic hepatitis B in adulthood
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25068
Abstract: Selection of HBeAg defective HBV mutants (mt) during childhood might influence infection outcome in adults. Aim of this study was to correlate the dynamics of pre‐core HBV mutant (pre‐C mt) selection with virological/clinical outcomes in… read more here.
Keywords: hbv; pre; hbeag negative; negative chronic ... See more keywords
Chronic viral HBeAg-negative hepatitis B: Epidemiological, clinical and biochemical characteristics in an outpatient descriptive cohort in Burkina Faso
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Epidemiology and Global Health"
DOI: 10.1016/j.cegh.2021.100799
Abstract: Abstract Introduction Our study aimed to describe epidemiological and diagnostic features in an outpatient's cohort with chronic HBeAg-negative hepatitis B. Patients and methods A cross-sectional descriptive study with a retrospective data collection was implemented from… read more here.
Keywords: hbeag; burkina faso; negative hepatitis; hbeag negative ... See more keywords
Hepatitis B core‐related antigen monitoring during peginterferon alfa treatment for HBeAg‐negative chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13117
Abstract: Serum Hepatitis B core‐related antigen (HBcrAg) level moderately correlates with cccDNA. We examined whether HBcrAg can add value in monitoring the effect of peginterferon (PEG‐IFN) therapy for HBeAg‐negative chronic hepatitis B (CHB) infection. Thus, serum… read more here.
Keywords: hepatitis; hbeag negative; decline; hbcrag ... See more keywords
p38 mitogen‐activated protein kinase impairment of innate immune cells is a characteristic feature of HBeAg‐negative chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13209
Abstract: The mitogen‐activated protein kinase p38 (MAPK) is implicated in the induction of immune responses by regulating the differentiation of T lymphocytes and production of cytokines. Our aim was to investigate p38MAPK phosphorylation in different stages… read more here.
Keywords: hepatitis; hbeag negative; p38; negative chronic ... See more keywords
Predictors of hepatitis B surface antigen loss, relapse and retreatment after discontinuation of effective oral antiviral therapy in noncirrhotic HBeAg‐negative chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13211
Abstract: Reliable predictors of outcomes after treatment discontinuation in HBeAg‐negative chronic hepatitis B (CHB) patients have not been established. We investigated the role of hepatitis B surface antigen (HBsAg), interferon‐inducible protein‐10 (IP10) and hepatitis B core‐related… read more here.
Keywords: loss relapse; hepatitis; hbsag loss; hbeag negative ... See more keywords
Predictive Value of HBsAg for Off-treatment Response in HBeAg-negative Chronic Hepatitis B Patients.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP"
DOI: 10.29271/jcpsp.2023.01.47
Abstract: OBJECTIVE To investigate the virological relapse (VR) rate and prognostic value of the HBsAg level at treatment completion for predicting sustained off-treatment response in HBeAg-negative patients after neucleos(t)ide analog (NA) therapy. STUDY DESIGN Prospective observational… read more here.
Keywords: negative chronic; hbeag negative; treatment; treatment response ... See more keywords
HBeAg-Negative/Anti-HBe-Positive Chronic Hepatitis B: A 40-Year-Old History
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DOI: 10.3390/v14081691
Abstract: Hepatitis B “e” antigen (HBeAg) negative chronic hepatitis B (CHB), 40 years since discovery in the Mediterranean area, has become the most prevalent form of HBV-induced liver disease worldwide and a major health care burden… read more here.
Keywords: negative anti; hbv; hbeag negative; chronic hepatitis ... See more keywords
Total serum bile acids predict therapy for HBeAg-negative chronic hepatitis B patients with borderline ALT and high HBV DNA.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of infection in developing countries"
DOI: 10.3855/jidc.15915
Abstract: INTRODUCTION The introduction of antiviral therapy in chronic hepatitis B (CHB) infection depends on precise evaluation of hepatic lesions. Total serum bile acids (TSBAs) are highly sensitive in monitoring liver dysfunction. We evaluated the predictive… read more here.
Keywords: hbeag negative; hbeag; hepatitis; hbv dna ... See more keywords
Characteristics of an Outpatient Cohort with HBeAg-Negative Chronic Hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Open Access Macedonian Journal of Medical Sciences"
DOI: 10.3889/oamjms.2019.623
Abstract: BACKGROUND: Patients with hepatitis Be antigen-negative chronic hepatitis B (HBeAg-negative CHB), and patients’ inactive carriers (IC) have similar laboratory and serologic characteristics and are not always easy to distinguish. AIM: To characterise hepatitis Be antigen… read more here.
Keywords: hepatitis; serology; hbeag negative; negative chronic ... See more keywords