Lewis b antigen is a common ligand for genogroup I norovirus strains
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13455
Abstract: Noroviruses are major causative agents of nonbacterial acute gastroenteritis in humans. Ten genogroups of noroviruses have been identified to date, among which genogroup I (GI) and genogroup II (GII) noroviruses are major pathogens for humans.… read more here.
Keywords: antigen common; lewis antigen; common ligand; genogroup ... See more keywords
Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.01833-22
Abstract: Human noroviruses are highly contagious and a major problem in closed institutions, such as schools, hospitals, and cruise ships. Reducing norovirus infections is challenging on multiple levels and includes the frequent emergence of antigenic variants,… read more here.
Keywords: hbga; nanobodies bound; norovirus; histo blood ... See more keywords
Human Norovirus Neutralized by a Monoclonal Antibody Targeting the Histo-Blood Group Antigen Pocket
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.02174-18
Abstract: The emergence of new epidemic GII.4 norovirus variants is thought to be associated with changes in antigenicity and HBGA binding capacity. Here, we show that HBGA binding profiles remain unchanged between the 1974 and 2012… read more here.
Keywords: hbga; hbga pocket; gii; norovirus ... See more keywords