Bosentan Attenuates Sickle Cell Disease Erythrocyte HbS Polymerization and Impaired Deformability Induced by Endothelin-1.
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DOI: 10.1139/cjpp-2022-0012
Abstract: The effects of endothelin-1 (ET-1) on erythrocytes from sickle cell disease (SCD) patients have been described, but mechanisms of ET-1 regarding primary erythrocyte functions remain unknown. ET-1 is a vasoconstrictor peptide produced by endothelial cells,… read more here.
Keywords: hbs polymerization; deformability; erythrocyte; sickle cell ... See more keywords