Long‐term outcomes and predictive scores for hepatocellular carcinoma and hepatitis B surface antigen seroclearance after hepatitis B e‐antigen seroclearance
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29874
Abstract: The significance of hepatitis B e‐antigen (HBeAg) seroclearance (ESC) in the long term is not well defined. The current study aimed to determine the clinical outcomes, the factors and predictive scores for hepatocellular carcinoma (HCC),… read more here.
Keywords: hepatitis; esc; antigen; predictive scores ... See more keywords
HBV transcription and translation persist despite viral suppression in HBV‐HIV co‐infected patients on antiretroviral therapy
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32634
Abstract: Background and aims: Liver injury may persist in patients with HBV receiving antiviral therapy who have ongoing transcription and translation. We sought to assess ongoing HBV transcription by serum HBV RNA, translation by serum hepatitis… read more here.
Keywords: hbv rna; hiv; hbsag; hbv ... See more keywords
HBsAg mutations related to occult hepatitis B virus infection in HIV‐positive patients result in a reduced secretion and conformational changes of HBsAg
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Virology"
DOI: 10.1002/jmv.24623
Abstract: Background: Occult hepatitis B infection (OBI) is a frequent finding in human immunodeficiency virus (HIV)‐infected patients. While several related mutations in the hepatitis B virus (HBV) genome have been reported, their distinct impact on HBsAg… read more here.
Keywords: hiv; occult hepatitis; conformational changes; hepatitis virus ... See more keywords
Resolution of HBV infection occurs sooner than recovery of renal disease in adult serum HBsAg‐negative HBV–associated glomerulonephritis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25211
Abstract: Most cases of hepatitis B virus–associated glomerulonephritis (HBV‐GN) occur in children and present with serum HBsAg positivity. Few studies have investigated adult patients with HBV‐GN who are serum HBsAg‐negative. This study aimed to determine the… read more here.
Keywords: adult; hbsag negative; serum hbsag; hbv ... See more keywords
Ubiquitin E3 ligase β‐TrCP negatively regulates surface protein of hepatitis B virus
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28620
Abstract: Chronic hepatitis B (CHB) still cannot be cured currently, while the pursuit of a functional cure seems to be an accessible goal, in which the condition mainly depends on the serum hepatitis B surface antigen… read more here.
Keywords: hbsag; trcp; ubiquitin ligase; hbsag levels ... See more keywords
Risk of viral reactivation in patients with occult hepatitis B virus infection during ruxolitinib treatment
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Hematology"
DOI: 10.1007/s00277-018-3405-7
Abstract: Dear Editor, Janus kinases (JAKs) are a family of cytoplasmic non-receptor tyrosine kinases (JAK1, JAK2, JAK3, TYK2) associated with cytokine receptors lacking intrinsic kinase activities. Ligand binding to these cytokine receptors activates JAKs, resulting in… read more here.
Keywords: dna; treatment; hbv; reactivation ... See more keywords
Generation of HBsAg DNA aptamer using modified cell-based SELEX strategy.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-020-05995-2
Abstract: Aptamers as potential alternatives for antibodies could be employed against hepatitis B surface antigen (HBsAg), the great hallmark and first serological marker in HBV, for further theragnostic applications. Therefore, isolation HBsAg specific aptamer was performed… read more here.
Keywords: based selex; modified cell; cell selex; cell based ... See more keywords
Design of aptamer-based sensing platform using gold nanoparticles functionalized reduced graphene oxide for ultrasensitive detection of Hepatitis B virus
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Papers"
DOI: 10.1007/s11696-020-01292-1
Abstract: In the present work, electrochemical aptasensor for earlier detection of Hepatitis B virus infection was developed. First, the surface of a glassy carbon electrode was modified with gold nanoparticles functionalized reduced graphene oxide, then thiol-terminated… read more here.
Keywords: detection; gold nanoparticles; aptasensor; detection hepatitis ... See more keywords
Use of HBsAg quantification in the natural history and treatment of chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology International"
DOI: 10.1007/s12072-019-09998-5
Abstract: In patients with chronic hepatitis B (CHB) infection, it is important to monitor the natural history, assess treatment response, and predict the risk of liver-related complications. Quantification of serum hepatitis B surface antigen (HBsAg) has… read more here.
Keywords: hepatitis; treatment; natural history; chronic hepatitis ... See more keywords
HBsAg mRNA degradation induced by a dihydroquinolizinone compound depends on the HBV posttranscriptional regulatory element
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.11.009
Abstract: ABSTRACT In pursuit of novel therapeutics targeting the hepatitis B virus (HBV) infection, we evaluated a dihydroquinolizinone compound (DHQ‐1) that in the nanomolar range reduced the production of virion and surface protein (HBsAg) in tissue… read more here.
Keywords: rna; hbv; regulatory element; hbsag mrna ... See more keywords
Hepatitis B infection in Mexican adults: results of a nationally representative survey.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of hepatology"
DOI: 10.1016/j.aohep.2021.100583
Abstract: INTRODUCTION AND OBJECTIVES . Hepatitis B virus (HBV) infection can lead to cirrhosis, hepatocellular carcinoma, and death if untreated. In Mexico, HBV vaccination for all children and adolescents was implemented in 1999. In 2000 the… read more here.
Keywords: hepatitis; infection; survey; prevalence ... See more keywords