Circulating microRNA‐122 levels are important predictor of hepatitis B virus surface antigen seroclearance
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25238
Abstract: It is currently unclear what impact serum microRNA‐122 (miR‐122) levels have on clearance of hepatitis B virus (HBV) surface antigen (HBsAg) in HBV‐infected patients who had not received antiviral therapy. The current study evaluated the… read more here.
Keywords: antigen; mir 122; serum mir; seroclearance ... See more keywords
Anti-HBc IgG Levels: A Predictor of HBsAg Seroclearance in Chronic Hepatitis B Patients with Nucleos(t)ide Analogue-Induced HBeAg Seroclearance
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-06845-2
Abstract: We investigated the efficiency of the indirect ratio of anti-HBc IgG at predicting HBsAg seroclearance in patients with nucleos(t)ide analogue (NA)-induced HBeAg seroclearance. We performed a retrospective study that included 366 chronic hepatitis B patients… read more here.
Keywords: seroclearance; anti hbc; hbc igg; hbsag seroclearance ... See more keywords
Durability of hepatitis B surface antigen seroclearance in untreated and nucleos(t)ide analogue-treated patients.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2017.09.018
Abstract: BACKGROUND & AIMS It is uncertain if nucleos(t)ide analogue (NA)-induced hepatitis B surface antigen (HBsAg) seroclearance is durable. We investigated the impact of hepatitis B surface antibody (anti-HBs) and duration of consolidation antiviral therapy on… read more here.
Keywords: hepatitis surface; seroclearance; nucleos ide; hbsag seroclearance ... See more keywords
Factors Associated With Rates of HBsAg Seroclearance in Adults With Chronic HBV Infection: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2018.10.027
Abstract: BACKGROUND & AIMS Seroclearance of hepatitis B surface antigen (HBsAg) is a marker for clearance of chronic hepatitis B virus (HBV) infection, but reported annual incidence rates of HBsAg seroclearance vary. We performed a systematic… read more here.
Keywords: hbv infection; seroclearance; systematic review; hbsag seroclearance ... See more keywords
A scoring system to predict HBsAg seroclearance in hepatitis B and C coinfected patients treated with interferon and ribavirin in an Asian cohort
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013383
Abstract: Abstract Current guidelines recommend that patients with hepatitis B virus-hepatitis C virus (HBV-HCV) coinfection be treated with direct anti-viral agents (DAAs). Compared with DAAs, pegylated interferon (PEG-IFN) and ribavirin therapy has the advantages of treating… read more here.
Keywords: risk; ribavirin; scoring system; cohort ... See more keywords
When can we stop nucleoside analogues in patients with chronic hepatitis B?
Sign Up to like & getrecommendations! Published in 2017 at "Liver International"
DOI: 10.1111/liv.13314
Abstract: Treatment with nucleoside analogue (NAs) is now the most common treatment for chronic hepatitis B (CHB) and is recommended by all guidelines. Stopping NAs is a controversial issue in these patients, unless the clinical endpoints… read more here.
Keywords: treatment; relapse; chronic hepatitis; hbeag seroconversion ... See more keywords
Discontinuation of nucleos(t)ide analogues is not associated with a higher risk of HBsAg seroreversion after antiviral-induced HBsAg seroclearance: a nationwide multicentre study
Sign Up to like & getrecommendations! Published in 2020 at "Gut"
DOI: 10.1136/gutjnl-2019-320015
Abstract: Objective Direct comparison of the clinical outcomes between nucleos(t)ide analogue (NA) discontinuation versus NA continuation has not been performed in patients with chronic hepatitis B who achieved HBsAg-seroclearance. Whether NA discontinuation was as safe as… read more here.
Keywords: hbsag reversion; continuation; associated higher; discontinuation ... See more keywords
Risk of hepatocellular carcinoma after spontaneous and nucleos(t)ide analogue induced hepatitis B surface antigen seroclearance.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e16162
Abstract: e16162 Background: Despite a favorable clinical course, the risk of hepatocellular carcinoma (HCC) still exists in patients achieving HBsAg seroclearance. Therefore, we investigated the incidence of HCC after spontaneous and nucleos(t)ide analogue (NA) induced HBsAg… read more here.
Keywords: induced hbsag; hcc; incidence; seroclearance ... See more keywords
Long-term Hepatitis B Surface Antigen Profile and Seroclearance after Severe Acute Flares of Chronic Hepatitis B
Sign Up to like & getrecommendations! Published in 2022 at "Gut and Liver"
DOI: 10.5009/gnl220122
Abstract: Background/Aims Hepatitis B surface antigen (HBsAg) seroclearance remains uncommon in chronic hepatitis B (CHB) infection. During acute flares of CHB (AFOCHB), alanine aminotransferase elevation reflects a mounting immune response toward viral clearance. We hypothesized that… read more here.
Keywords: group; severe afochb; hepatitis; hbsag seroclearance ... See more keywords