In vivo characterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2016.10.008
Abstract: BACKGROUND The recently diagnosed leukodystrophy Hypomyelination with Brain stem and Spinal cord involvement and Leg spasticity (HBSL) is caused by mutations of the cytoplasmic aspartyl-tRNA synthetase geneDARS. The physiological role of DARS in translation is… read more here.
Keywords: aspartyl trna; trna synthetase; leukodystrophy; mice ... See more keywords