Abstract P1107: Acute Psychosocial Stress Increases Circulating Inflammatory Mediators in the Humanized Sickle Cell Mouse Model
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hyp.74.suppl_1.p1107
Abstract: Vaso-occlusive crisis often occurs in sickle cell disease (SCD). Since psychosocial stress leads to impaired vascular function and inflammation, we hypothesized that acute psychosocial stress elicits an exaggerated blood pressure response and/or increased circulating inflammatory… read more here.
Keywords: hbss; psychosocial stress; inflammatory mediators; hbaa ... See more keywords
Inhibition of DAGLĪ² as a therapeutic target for pain in sickle cell disease
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DOI: 10.3324/haematol.2021.280460
Abstract: Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized… read more here.
Keywords: disease; hyperalgesia; sickle; hbss ... See more keywords
Discrete Element Modeling of the Effect of Hydrate Distribution Heterogeneity on the Mechanical Behavior of Cemented Hydrate-Bearing Sediments
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DOI: 10.3390/jmse11040831
Abstract: Hydrate distribution heterogeneity is often observed in natural and artificial hydrate-bearing sediments (HBSs). To capture hydrate distribution heterogeneity, a pore-scale method is proposed to model cemented HBSs using the discrete element method (DEM). This method… read more here.
Keywords: hydrate distribution; hbss; distribution heterogeneity; hydrate ... See more keywords