Getting to HBV cure: The promising paths forward
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32314
Abstract: Chronic HBV infection is a global public health burden estimated to impact nearly 300 million persons worldwide. Despite the advent of potent antiviral agents that effectively suppress viral replication, HBV cure remains difficult to achieve… read more here.
Keywords: cure promising; promising paths; cure; hbv cure ... See more keywords
Pathway to global elimination of hepatitis B: HBV cure is just the first step.
Sign Up to like & getrecommendations! Published in 2023 at "Hepatology"
DOI: 10.1097/hep.0000000000000430
Abstract: Hepatitis B (HBV) is a major cause of global morbidity and mortality and the lead cause of liver cancer worldwide. Significant advances have recently been made towards development of a finite HBV treatment that achieves… read more here.
Keywords: hbv cure; elimination; cure; hepatitis hbv ... See more keywords
Meeting the Challenge of Eliminating Chronic Hepatitis B Infection
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DOI: 10.3390/genes10040260
Abstract: Over 257 million people live with chronic hepatitis B virus (HBV) infection and there is no known cure. The effective preventative vaccine has no impact on existing infection. Despite the existence of drugs which efficiently… read more here.
Keywords: hbv cure; infection; meeting challenge; chronic hepatitis ... See more keywords
Recent Progress and Future Prospective in HBV Cure by CRISPR/Cas
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DOI: 10.3390/v14010004
Abstract: Hepatitis B virus (HBV) infection remains an important issue of global public health. Although current antiviral therapy has dramatically reduced the mortality and morbidity of chronic hepatitis B (CHB), it fails to cure it. Rebound… read more here.
Keywords: delivery; hbv cure; crispr; therapy ... See more keywords
HBsAg Loss as a Treatment Endpoint for Chronic HBV Infection: HBV Cure
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14040657
Abstract: Despite the availability of effective vaccines and antiviral therapy over the past two to three decades, chronic hepatitis B virus (HBV) infection remains a major global health threat as a leading cause of cirrhosis and… read more here.
Keywords: hbsag loss; hbv infection; hbv; cure ... See more keywords