Less can be more: A finite treatment approach for HBeAg‐negative chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29821
Abstract: Long-term administration of potent nucleos (t)ide analogs (NAs) is the cornerstone of antiviral therapy for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B, as it reduces liver-related complications by efficiently suppressing viral replication. Although there… read more here.
Keywords: hepatitis; hbeag negative; relapse; negative chronic ... See more keywords
Letter to the editor: Alu‐PCR design may have compromised detection of integrated core HBV DNA
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32473
Abstract: To the editor, In their recent paper, Erken et al. used AluPCR to quantify integrated HBV DNA in liver tissue and report that the amount of integrations correlated with HBeAg status.[1] Their findings are important… read more here.
Keywords: integrated hbv; dna; integrated core; hbv dna ... See more keywords
Letter to the editor: HBeAg expression suppressing/abolishing mutation elevated HBV DNA level in HBeAg‐negative patients with chronic HBV infection
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32508
Abstract: To the editor, We read with great interest the article by Lau et al.,[1] which demonstrated the prevalence of HBV precore G1896A and basal core promoter (BCP) A1762T and G1764A variants and revealed relatively elevated… read more here.
Keywords: a1762t g1764a; dna level; g1764a mutation; hbv dna ... See more keywords
A3G‐induced mutations show a low prevalence and exhibit plus‐strand regional distribution in hepatitis B virus DNA from patients with non‐hepatocellular carcinoma (HCC) and HCC
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26418
Abstract: APOBEC3G (A3G) cytidine deaminase is an innate immune restriction factor that can edit and inhibit hepatitis B virus (HBV) replication. The preferred target of A3G is deamination of the third cytosine of 5′CCC to form… read more here.
Keywords: induced mutations; hcc; dna; a3g induced ... See more keywords
Nucleos(t)ide analogues altered quasispecies composition of hepatitis B virus (HBV)‐resistant mutations in serum HBV DNA and serum HBV RNA
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28612
Abstract: Serum hepatitis B virus (HBV) RNA is a new serological indicator reflecting viral replication with good clinical application prospects. This study aimed to clarify the dynamic changes of serum HBV RNA levels and the quasispecies… read more here.
Keywords: hbv rna; hbv dna; serum hbv;
Hepatitis B virus core‐related antigen (HBcrAg) as a prognostic marker for the development of hepatocellular carcinoma: A mini systematic review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2353
Abstract: Chronic hepatitis B (CHB) infection is a risk factor for hepatocellular carcinoma (HCC). Previous studies showed that elevated levels of Hepatitis B Virus (HBV) DNA and HBsAg are associated with increased HCC risk in patients… read more here.
Keywords: hepatocellular carcinoma; hcc; hbcrag; hepatitis ... See more keywords
Risk of viral reactivation in patients with occult hepatitis B virus infection during ruxolitinib treatment
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Hematology"
DOI: 10.1007/s00277-018-3405-7
Abstract: Dear Editor, Janus kinases (JAKs) are a family of cytoplasmic non-receptor tyrosine kinases (JAK1, JAK2, JAK3, TYK2) associated with cytokine receptors lacking intrinsic kinase activities. Ligand binding to these cytokine receptors activates JAKs, resulting in… read more here.
Keywords: dna; treatment; hbv; reactivation ... See more keywords
Quantification of intrahepatic total HBV DNA in liver biopsies of HBV-infected patients by a modified version of COBAS® Ampliprep/COBAS®TaqMan HBV test v2.0
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DOI: 10.1007/s00430-017-0504-3
Abstract: Abstract Intrahepatic total HBV DNA (it-HBV DNA) level might reflect the size of virus reservoir and correlate with the histological status of the liver. To quantitate it-HBV DNA in a series of 70 liver biopsies… read more here.
Keywords: cobas; hbv dna; hbv; liver biopsies ... See more keywords
Benefit of Antiviral Therapy for HBV-Related HCC with Undetectable HBV DNA Is Still Dubious
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DOI: 10.1007/s10620-022-07383-1
Abstract: Hepatitis B virus (HBV) is an important risk factor for hepatocellular carcinoma (HCC) as it can lead to the development of HCC even in the absence of cirrhosis [1]. In the development of HCC, treatment… read more here.
Keywords: hbv dna; hcc; hbv reactivation; hbv ... See more keywords
Impact of Preoperative Hepatitis B Virus Levels on Prognosis After Primary and Repeat Hepatectomies for Hepatocellular Carcinoma Patients—a Retrospective Study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-017-3638-0
Abstract: BackgroundChronic HBV plays an important role in hepatocellular carcinoma pathogenesis. Previously, most studies have been focusing on HBV DNA levels before the primary curative hepatectomy. However, the association of virus level before repeat hepatectomy with… read more here.
Keywords: hepatocellular carcinoma; repeat; repeat hepatectomies; primary repeat ... See more keywords
A target-triggered biosensing platform for detection of HBV DNA based on DNA walker and CHA.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2018.05.024
Abstract: Hepatitis B virus (HBV), one of the causative agents of viral hepatitis, may lead to chronic hepatitis, cirrhosis, and liver cancer. In this work, we designed a sensitive and modular biosensing platform for detecting HBV… read more here.
Keywords: detection; dna; dna walker; hbv dna ... See more keywords