Insights From Deep Sequencing of the HBV Genome—Unique, Tiny, and Misunderstood
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DOI: 10.1053/j.gastro.2018.07.058
Abstract: Hepatitis B virus (HBV) is a unique, tiny, partially double-stranded, reverse-transcribing DNA virus with proteins encoded by multiple overlapping reading frames. The substitution rate is surprisingly high for a DNA virus, but lower than that… read more here.
Keywords: deep sequencing; hbv; unique tiny; insights deep ... See more keywords
Integrating nested PCR with high-throughput sequencing to characterize mutations of HBV genome in low viral load samples
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DOI: 10.1097/md.0000000000007588
Abstract: Abstract Due to the low viral load of hepatitis B virus (HBV) in plasma samples, conventional techniques have limitations to the detection of antiviral resistance mutations. To solve the problem, we developed a fast, highly… read more here.
Keywords: low viral; load samples; viral load; load ... See more keywords