REP 2139: Antiviral Mechanisms and Applications in Achieving Functional Control of HBV and HDV Infection.
Sign Up to like & getrecommendations! Published in 2019 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.8b00156
Abstract: Nucleic acid polymers (NAPs) are broad spectrum antiviral agents whose antiviral activity in hepatitis B virus (HBV) infection is derived from their ability to block the release of the hepatitis B virus surface antigen (HBsAg).… read more here.
Keywords: hbv hdv; infection; hbv; rep 2139 ... See more keywords
Interactions of Na+/taurocholate cotransporting polypeptide with host cellular proteins upon hepatitis B and D virus infection: novel potential targets for antiviral therapy
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DOI: 10.1515/hsz-2022-0345
Abstract: Abstract Na+/taurocholate cotransporting polypeptide (NTCP) is a member of the solute carrier (SLC) family 10 transporters (gene symbol SLC10A1) and is responsible for the sodium-dependent uptake of bile salts across the basolateral membrane of hepatocytes.… read more here.
Keywords: hepatitis; infection; virus; hbv hdv ... See more keywords
HBV/HDV Co-Infection: Epidemiological and Clinical Changes, Recent Knowledge and Future Challenges
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DOI: 10.3390/life11020169
Abstract: Several investigations have been published on Hepatitis Delta Virus (HDV) infection in recent years, from which we have drawn the salient data to provide readers with useful information to improve their knowledge on the subject.… read more here.
Keywords: hbv hdv; infection epidemiological; knowledge; hdv ... See more keywords
Discontinuation of Passive Immunization Is Safe after Liver Transplantation for Combined HBV/HDV Infection
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DOI: 10.3390/v13050904
Abstract: Patients after LT due to combined HBV/HDV infection are considered to be high-risk patients for recurrence of hepatitis B and D. To date, life-long prophylaxis with hepatitis B immunoglobulin (HBIG) and replication control with nucleos(t)ide… read more here.
Keywords: hbv hdv; discontinuation; hdv infection; combined hbv ... See more keywords
IFITM3 Interacts with the HBV/HDV Receptor NTCP and Modulates Virus Entry and Infection
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DOI: 10.3390/v14040727
Abstract: The Na+/taurocholate co-transporting polypeptide (NTCP, gene symbol SLC10A1) is both a physiological bile acid transporter and the high-affinity hepatic receptor for the hepatitis B and D viruses (HBV/HDV). Virus entry via endocytosis of the virus/NTCP… read more here.
Keywords: infection; hbv hdv; virus entry; ifitm3 ... See more keywords
Key Factors for “Fishing” NTCP as a Functional Receptor for HBV and HDV
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DOI: 10.3390/v15020512
Abstract: About ten years ago, Wenhui Li’s research group in China identified the sodium taurocholate co-transporting polypeptide (NTCP), a bile acid transporter predominantly expressed in the liver, as a functional receptor for hepatitis B virus (HBV)… read more here.
Keywords: functional receptor; hbv; factors fishing; hbv hdv ... See more keywords