Pacbio Sequencing of PLC/PRF/5 Cell Line and Clearance of HBV Integration Through CRISPR/Cas-9 System
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.676957
Abstract: The integration of HBV DNA is one of the carcinogenic mechanisms of HBV. The clearance of HBV integration in hepatocyte is of great significance to cure chronic HBV infection and thereby prevent the occurrence of… read more here.
Keywords: plc prf; hbv integration; integration; hbv ... See more keywords
Different types of viral-host junction found in HBV integration breakpoints in HBV-infected patients
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.9709
Abstract: The present study surveyed the characteristics of hepatitis B virus (HBV) integration in the liver genomes of patients with acute hepatitis B (AHB), carriers of inactive hepatitis B surface antigen (HBsAg), and patients with chronic… read more here.
Keywords: integration breakpoints; viral host; hbv integration; integration ... See more keywords
DNA methylation at hepatitis B virus integrants and flanking host mitochondrially encoded cytochrome C oxidase III
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13544
Abstract: It is widely accepted that hepatitis B virus (HBV) integrants in the human genome are one of the key factors in liver carcinogenesis. Although it is difficult to observe pre/post-HBV infection genomic-level changes in the… read more here.
Keywords: hbv; dna methylation; integration; mitochondrially encoded ... See more keywords