Articles with "hbw 3220" as a keyword



Abstract CT147: Phase I clinical study of Bruton’s tyrosine kinase inhibitor (BTKi) HBW-3220 capsules in patients with relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL)

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-ct147

Abstract: Purpose: This clinical study is to evaluate HBW-3220, a novel reversible BTK inhibitor (BTKi) with an improved in vitro profile than the existing non-covalent drugs pirtobrutinib (LOXO-305, approved) and MK-1026 (Phase III). HBW-3220 shows superior… read more here.

Keywords: hbw 3220; cell; lymphoma; study ... See more keywords