Autophagic protein ULK1 regulates FOXM1 signalling in human hepatoma cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.08.068
Abstract: Hepatocellular cancer (HCC) is one of the leading causes of mortality worldwide. Unfortunately, a limited choice of anti-cancer drugs is available for treatment, owing to their minimal efficacy and development of acquired resistance. Autophagy, a… read more here.
Keywords: ulk1 regulates; hcc progression; protein ulk1; autophagy ... See more keywords
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos.
Sign Up to like & getrecommendations! Published in 2023 at "Gut"
DOI: 10.1136/gutjnl-2022-327998
Abstract: Objective Growing evidence indicates that tumour cells exhibit characteristics similar to their lineage progenitor cells. We found that S100 calcium binding protein A10 (S100A10) exhibited an expression pattern similar to that of liver progenitor genes.… read more here.
Keywords: hcc progression; s100a10; extracellular vesicles; progression ... See more keywords
miR-200a-3p- and miR-181-5p-Mediated HOXB5 Upregulation Promotes HCC Progression by Transcriptional Activation of EGFR
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.822760
Abstract: Background Hepatocellular carcinoma (HCC) remains a worldwide burden. However, the mechanisms behind the malignant biological behavior of HCC remain unclear. The homeobox (HOX) family could act as either promoters or suppressors in different kinds of… read more here.
Keywords: hcc progression; mir 181; 200a mir; mir ... See more keywords