Risk factors for HCC in contemporary cohorts of patients with cirrhosis
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32434
Abstract: Background and Aims: Etiological risk factors for cirrhosis have changed in the last decade. It remains unclear to what extent these trends in cirrhosis risk factors have changed HCC risk. Approach and Results: We used… read more here.
Keywords: patients cirrhosis; hcc risk; risk factors; risk ... See more keywords
Untargeted plasma metabolomics for risk prediction of hepatocellular carcinoma: A prospective study in two Chinese cohorts
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34229
Abstract: Characterization of metabolic perturbation prior to hepatocellular carcinoma (HCC) may deepen the understanding of causal pathways and identify novel biomarkers for early prevention. We conducted two 1:1 matched nested case‐control studies (108 and 55 pairs)… read more here.
Keywords: hepatocellular carcinoma; plasma metabolomics; hcc risk; risk ... See more keywords
The association of lncRNA-HULC polymorphisms with hepatocellular cancer risk and prognosis.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.05.096
Abstract: BACKGROUND Genetic polymorphisms in lncRNA HULC may affect the susceptibility and clinical outcome of cancer. We aimed to investigate the association of HULC tagSNPs with the risk and prognosis of hepatocellular cancer, as well as… read more here.
Keywords: risk; hulc; hcc risk; lncrna hulc ... See more keywords
Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abo4474
Abstract: Prediction of hepatocellular carcinoma (HCC) risk is an urgent unmet need in patients with nonalcoholic fatty liver disease (NAFLD). In cohorts of 409 patients with NAFLD from multiple global regions, we defined and validated hepatic… read more here.
Keywords: nonalcoholic fatty; hepatocellular carcinoma; disease; hcc ... See more keywords
Correlation of DEPDC5 rs1012068 and rs5998152 Polymorphisms with Risk of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Oncology"
DOI: 10.1155/2023/5957481
Abstract: Background Emerging evidence has shown that two common genetic polymorphisms within the pleckstrin domain-containing protein 5 (DEPDC5), rs1012068 and rs5998152, may be associated with the risk of hepatocellular carcinoma (HCC), especially in those individuals chronically… read more here.
Keywords: rs1012068 rs5998152; hcc risk; depdc5 rs1012068; risk ... See more keywords
Tenofovir is superior to entecavir in reducing HCC for patients with HBV-related compensated cirrhosis at high HCC risk scores
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Chronic Disease"
DOI: 10.1177/20406223221102791
Abstract: Background: Both tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are known to reduce the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). This study aimed to compare the difference in HCC… read more here.
Keywords: compensated cirrhosis; hcc; hcc risk; group ... See more keywords
BRIP1 coding variants are associated with a high risk of hepatocellular carcinoma occurrence in patients with HCV- or HBV-related liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.11327
Abstract: The molecular mechanisms of hepatocellular carcinoma (HCC) carcinogenesis are still not fully understood. DNA repair defects may influence HCC risk. The aim of the study was to look for potential genetic variants of DNA repair… read more here.
Keywords: liver disease; brip1; risk; hcc risk ... See more keywords
Association of twelve polymorphisms in three onco-lncRNA genes with hepatocellular cancer risk and prognosis: A case-control study
Sign Up to like & getrecommendations! Published in 2018 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v24.i23.2482
Abstract: AIM To evaluate the association of 12 tag single nucleotide polymorphisms (tagSNPs) in three onco-long non-coding RNA (lncRNA) genes (HOTTIP, CCAT2, MALAT1) with the risk and prognosis of hepatocellular cancer (HCC). METHODS Twelve tagSNPs covering… read more here.
Keywords: risk; prognosis; hcc risk; hottip ... See more keywords