Analytical characterization of host-cell-protein-rich aggregates in monoclonal antibody solutions.
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DOI: 10.1002/btpr.3343
Abstract: Host-cell proteins (HCPs) and high molecular weight (HMW) species have historically been treated as independent classes of impurities in the downstream processing of monoclonal antibodies (mAbs), but recent indications suggest that they may be partially… read more here.
Keywords: cell; hccf protein; protein eluate; host cell ... See more keywords